Source and full article In February 2012, the US Department of Health and Human Services added another layer of review for grant proposals involving GOF research, but only for H5N1; this was extended to H7N9 in August 2013. The research community became deeply polarized …
Source and full article The government has said that it would stockpile the antiviral drug oseltamivir (marketed by Roche as Tamiflu) again, despite large amounts of previously bought supplies being written off and questions raised by experts over its effectiveness, MPs have been told.
Source and full article Our theory of bridge communities may help guide prevention and explain historical emergence events, where disruption of stable economic, political or demographic processes reduced population viscosity at ecological interfaces.
Source and full article The molecular basis of adaptation and pathogenicity of H9N2 influenza virus in mammals is largely unknown. Here we show that a mouse-adapted PB2 gene with a phenylalanine-to-leucine mutation (F404L) mainly contributes to the enhanced polymerase activity, replication, and pathogenicity of H9N2 in mice,
Source and full article Virus isolates from patients in the same cluster shared high sequence similarities. In conclusion, although continually evolving the currently circulating H7N9 viruses in Guangdong province have not yet demonstrated the capacity for efficient and sustained person-to-person transmission.
Source and full article Antimicrobial-resistant bacteria. Our profligate and imprudent use of antibiotics has led to the emergence and spread of bacteria that resist their effect. MRSA, XTB and a gamut of other resistant infections are widespread and kill many thousands each …
Source and full article Particularly, the short- and long-term implications on export, that is, indirect consequential costs (ICC) and aftermath costs of these strategies, should be analysed further.
Source and full article It was concluded that the model creates economically relevant, adequate and credible output for subsequent use in economic analysis. A detailed economic analysis is presented in a subsequent article.
Source and full article Dissimilar HA subtypes tended to have different temporal occurrence within seasons, where the subtypes that dominated in early autumn were rare in late autumn, and vice versa. This suggests that build-up of herd immunity affected IAV dynamics in this system.
Source and full article Observational data arising from treatment of severely ill individuals support use of these drugs early in illness and show improvement in outcomes associated with drug use.