Source and full article Finally, simulated patterns of time allocation matched the interview data in a number of ways, suggesting that our framework constitutes a sound basis for simulating fine-scale movement and for investigating factors that influence it.

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Source and full article In its ongoing surveillance for H7N9 avian influenza in poultry, China’s agriculture ministry recently detected the virus in 14 samples from two provinces, according to a recent update from the World Health Organization’s (WHO’s) Western Pacific Region.

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Source and full article Live poultry markets, common throughout China, could potentially expose many residents to novel influenza viruses, according to results of a cross-sectional study.

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Source and full article These structural changes demonstrate plasticity in the PA-PB1 binding interface which may be exploited in the development of novel therapeutics.

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Source and full article Similarly we find distinct patterns among influenza proteins in H1N1 (a strain against which human populations rapidly developed immunity) and H5N1 and H7N9 (highly pathogenic avian flu strains, with significantly greater case mortality rates).

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Source and full article Our results are consistent with historic literature; although passerines and terrestrial wild birds may have a limited role in the epidemiology of IAV when associated with infected domestic poultry or other aberrant hosts, there is no evidence supporting their involvement as natural reservoirs for IAV.

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Source and full article We sampled 7,511 black-headed gulls for influenza virus in the Netherlands during 2006-2010 and found that subtypes H13 and H16 caused annual epidemics in fledglings on colony sites. Our findings validate targeted surveillance of wild waterbirds and clarify underlying factors for influenza virus emergence in other species.

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Avian Flu Diary: Vietnam Gears Up To Detect, Fight Avian H5N6

August 15, 2014

Source and full article Although its track record in infecting humans is limited to only one known case (see May 2014 Sichuan China: 1st Known Human Infection With H5N6 Avian Flu), the emergence of a highly pathogenic H5N6 virus on a poultry farm in China earlier this spring has raised concerns that we might have […]

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Online collaboration: Scientists and the social network : Nature News & Comment

August 14, 2014

Source and full article Giant academic social networks have taken off to a degree that no one expected even a few years ago. A Nature survey explores why.

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Influenza A virus Acquires Enhanced Pathogenicity and Transmissibility After Serial Passages in Swine

August 13, 2014

Source and full article Our findings suggest that pigs can readily induce adaptive mutational changes to a precursor pandemic-like virus to transform it into a highly virulent and infectious form akin to that of the pandemic H1N1/2009 virus which underlines the potential direct role of pigs in promoting influenza A virus pathogenicity and transmissibility.

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Using Clinician’s Search Query Data to Monitor Influenza Epidemics

August 13, 2014

Source and full article Search query information from a clinician’s database, UpToDate, is shown to timely predict influenza epidemics in the United States. Our results show that digital disease surveillance tools based on experts’ databases may be able to provide an alternative, reliable and stable signal for accurate predictions of flu outbreaks.

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Influenza Virus A/Anhui/1/2013 (H7N9) Replicates Efficiently in the Upper and Lower Respiratory Tracts of Cynomolgus Macaques

August 13, 2014

Source and full article From comparison with previous studies, we conclude that the emerging H7N9 influenza virus was more pathogenic in cynomolgus macaques than seasonal influenza A viruses and most isolates of the pandemic H1N1 virus but less pathogenic than the 1918 Spanish influenza virus or highly pathogenic avian influenza (HPAI) H5N1 virus.

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Avian Flu Diary: OIE: Two Outbreaks Of H5N6 In Vietnamese Poultry

August 13, 2014

Source and full article Today the OIE has published a notification of two – widely separated – H5N6 outbreaks in Vietnamese poultry. The first, located near the border with China, had an onset in April – and began at roughly the same time as China’s previously mentioned outbreak (albeit several hundred miles distant).

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Avian Flu Diary: mBio: The Pathogenicity Of Avian H7N9 In Cynomolgus Macaques

August 13, 2014

Source and full article Curiously, while more pathogenic to macaques than most strains of the 2009 H1N1 pandemic virus, and seasonal H3N2, the H7N9 virus produced less severe symptoms in these non-human primates than has been common observed in humans. The authors suggest that the high rate of co-morbidities in the – mostly elderly – […]

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Human case of H7N9 in China linked to outbreaks at poultry farm | Infectious Disease

August 12, 2014

Source and full article An epidemiological link has been identified between a human case of influenza A(H7N9) virus and a Chinese poultry farm, which yielded positive samples for H7N9 and H9N2 viruses, according to recent findings.

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Hajj pilgrimage led to acquisition, spread of respiratory infections

August 12, 2014

Source and full article Pilgrims embarking on the annual hajj to Saudi Arabia are at risk of contracting various respiratory infections during their journey and subsequently importing these infections to their home countries and contributing to the global spread of disease, according to recent findings.

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Police exposure to infectious agents: an audit of protective policies

August 11, 2014

Source and full article Police departments have opportunities to improve policies and practices for infection prevention and control. Accurate documentation of vaccination status is essential to ensure provision of appropriate post-exposure assessment and treatment. Better reporting of exposure will improve understanding of the infection transmission risk, enhancing the ability to offer targeted education and services […]

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